Caprion

Accelerating precision medicine™

Targeted MRM-Based Biomarker Panels

Caprion has extensive expertise in development of targeted biomarker assays using Multiple Reaction Monitoring (MRM) mass spectrometry. MRM, which was selected by Nature Methods as Method of the Year for 2012, facilitates rapid development of highly specific, antibody-free assays for quantitation of up to 100s of target proteins. Caprion uses stable isotope labeled peptides for each target peptide to facilitate robust quantitation and enhance reproducibility. Proteins for MRM assays can be selected from multiple sources, including proteomics, transcriptomics, literature, or pathway analyses.

Caprion offers both custom and off-the-shelf MRM assays to facilitate rapid screening and verification of candidate biomarkers. Once the most robust biomarkers have been selected, MRM assays can be further developed as fit-for-purpose assays to meet regulatory requirements.

Applications

Caprion’s MRM-based approach facilitates rapid development of highly specific, multiplexed assays for biomarker discovery and development

  • Custom assays for rapid assessment of 100s of candidate biomarkers from literature, proteomics, transcriptomics, and other discovery platforms
  • Off-the-shelf panels for CNS, preclinical safety, diabetes and tuberculosis
  • Verification and refinement of multiplexed biomarker panels for diagnostics, patient stratification, efficacy etc.
  • Elucidation of underlying biology and mechanism of action

Benefits of Caprion’s Targeted Discovery Approach

Caprion offers both custom and off-the-shelf multiplexed assays for biomarker screening and verification. Our MRM mass spectrometry based platform features several advantages, including:

  • Rapid assay development, without the need for antibodies
  • Excellent sensitivity, specificity, and robustness
  • Highly-multiplexed assay for rapid, parallel assessment of 100s of proteins from a single sample
  • Easily converted to fit-for-purpose assays for non-clinical and clinical use

 


Caprion

Accreditations & Certifications

CAP accreditation and CLIA certification

CAP Accredited

Headquarters

+1 514.360.3600
+1 877.776.3443
141 President Kennedy Ave., Suite SB-5658
Montreal, Quebec
CANADA

USA

Primity Bio
48383 Fremont Blvd
Suite 118
Fremont, CA 94538
Tel.: +1 858.229.2529

Serametrix
2235 Farraday Ave,Suite N,
Carlsbad, CA, 92008, USA
Tel: +1 760 652 4060

HistoGeneX
1331 W 75th St #401,
Naperville, IL 60540, USA
Tel: +1 630-473-6655
info@histogenex.com

AUSTRALIA

Serametrix Party Limited
Suite 4/54-60 Briggs Street
Camperdown, NSW, 2050
Australia
+61 2 9168 5908

EUROPE

Caprion Biosciences Inc.
+32 (0) 71 96 23 36
8 rue Adrienne Bolland
6041 Gosselies
BELGIUM

Serametrix
Unit 22, Surrey Technology Centre,
40 Occam Road,
Guildford, Surrey, UK
GU2 7YG
Tel: +44 1483 685599

Antwerp, Belgium
HistoGeneX
Sint-Bavostraat 78
2610 Antwerpen (Wilrijk)
Belgium
Tel: +32 3 50 20 500
Sample Reception: +32 3 50 20 620
Shipments: +32 3 50 20 625

CANADA LAB

201 President Kennedy Ave., Suite PK-3900
Montreal, Quebec
CANADA
+1 514.360.3600
+1 877.776.3443



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Contact

+1 877.776.3443

info@caprion.com