Scientific publications
Proteomics
E. Gagnon, S. Duclos, C. Rondeau, E. Chevet, P.H. Cameron, O. Steele-Mortimer, J. Paiement, J.J.M. Bergeron, and M. Desjardins
Endoplasmic Reticulum-Mediated Phagocytosis Is a Mechanism of Entry into Macrophages
Cell (2002) 110: 119-131
M. Houde, S. Bertholet, E. Gagnon, S. Brunet, G. Goyette, A. Laplante, M.F. Princiotta, P. Thibault, D. Sacks, and M. Desjardins
Phagosomes are Competent Organelles for Antigen Cross-Presentation
Nature (2003) 425: 402-406
M. Desjardins
ER-Mediated Phagocytosis: A New Membrane for New Functions
Nature Reviews Immunology (2003) 3:280-291
J. Bergeron, M. Desjardins, P. Kearney and P. Thibault
Organelle Proteomics: Looking at Less to See More
Trends in Cell Biology (2003) 13: 629-638
P. Kearney and P. Thibault
Bioinformatics Meets Proteomics-Bridging the Gap Between Mass Spectrometry Data Analysis and Cell Biology
J. Bioinformatics and Computational Biology (2003) 1:183-200
P. Thibault, A. Martin, M. Gilbert, W.W. Wakarchuk, and J. C. Richards
Analysis of Bacterial Glycolipids by Capillary Electrophoresis-Electrospray Mass Spectrometry: Haemophilus influenzae and Neisseria meningitidis Lipopolysaccharides
Methods Mol. Biol. (2003) 213: 241-259
P. Kearney, D. Jaitly, R. Belanger, and P. Thibault
MS/MS Peak Identification and its Applications
Proceedings of Intelligent Systems for Molecular Biology (2004)
M.H. Fortier, E. Bonneil, P. Goodley, and P. Thibault
Integrated Microfluidic Device for Mass Spectrometry-Based Proteomics and Its Application to Biomarker Discovery Programs
Anal. Chem. (2005) 77: 1631-1640
K. Venne, E. Bonneil, K. Eng, and P. Thibault
Improvement in Peptide Detection for Proteomics Analysis Using NanoLC-MS and High-Field Asymmetry Waveform Ion Mobility Mass Spectrometry
Anal. Chem. (2005) 77: 2176-2186
E. Bonneil, S. Tessier, A. Carrier, P. Thibault
Multiplex Multidimensional NanoLC-MS System for Targeted Proteomic Analyses
Electrophoresis (2005) 26: 4575-4589
D. Sitnikov, D. Chan, E. Thibaudeau, M. Pinard, J.M. Hunter
Protein Depletion from Blood Plasma using a Volatile Buffer
J. Chromatog. B (2006) 832: 41-46
M.T. Follettie, M. Pinard, J.C. Keith, Jr., L. Wand, D. Chelsky, C. Hayward, P. Kearney, P. Thibault, E. Paramithiotis, A.J. Dorner, and H.A. Harris
Organ Messenger Ribonucleic Acid and Plasma Proteome Changes in the Adjuvant-Induced Arthritis Model: Responses to Disease Induction and Therapy with the Estrogen Receptor-b Selective Agonist ERB-041
Endocrinology (2006) 147: 714-723
K. Sircar, L. Gaboury, L. Ouadi, M. Mecteau, E. Scarlata, F. Saad, A. Aprikian, S. Tanguay, S. Lapointe, C. Lussier, T. Miletti, and J. Lanoix.
Isolation of human prostatic epithelial plasma membranes for proteomics using mirror image tissue banking of radical prostatectomy specimens.
Clin Cancer Res. (2006) 15: 4178-4184.
K. Lekpor, M.J. Benoit, H. Butler, M. Schirm, D. Vasilescu, K. Bonter, D. Chelsky, P. Hugo, J. Hunter, G. Opiteck, E. Paramithiotis, and P. Kearney.
An evaluation of multidimensional fingerprinting in the context of clinical proteomics. Proteomics Clin. Appll. (2007) 1:457-466
J. Lamontagne, H. Butler, E. Chaves-Olarte, J. Hunter, M. Schirm, C. Paquet, M. Tian, P. Kearney, L. Hamaidi, D. Chelsky, I. Moriyon, E. Moreno, and E. Paramithiotis.
Extensive cell envelope modulation is associated with virulence in Brucella abortus.
J. Prot. Res. (2007) 6:1519-1529
P. Kearney, H. Butler, K. Eng, and P. Hugo
Protein identification and peptide expression resolver: harmonizing protein identification with protein expression data
J. Prot. Res. (2008) 7:234-244
I. Jutras, M. Houde, N. Currier, J. Boulais, S. Duclos, S. LaBoissiere, E. Bonneil, P. Kearney, P. Thibault, E. Paramithiotis, P. Hugo, and M. Desjardins.
Modulation of the phagosome proteome by interferon-g.
Mol. Cell. Proteomics (2008) in press
Prions
E. Paramithiotis, M. Pinard, T. Lawton, S. LaBoissiere, V.L. Leathers, W-Q. Zou, L.A. Estey, J. Lamontagne, M.T.Lehto, L.H. Kondejewski, G.P. Francoeur, M. Papadopoulos, A. Haghighat, S.J. Spatz, M. Head, R. Will, J. Ironside, K. O’Rourke, Q. Tonelli, H.C.Ledebur, A. Chakrabartty, and N.R. Cashman
A Prion Protein Epitope Selective for the Pathologically Misfolded Conformation
Nature Medicine (2003) 9: 893-899
I.E. Mazzoni, H.C. Ledebur Jr., E. Paramithiotis, and N. Cashman
Lymphoid Signal Transduction Mechanisms Linked to Cellular Prion Protein
Biochemistry and Cell Biology (2005) 83: 644-653
Superoxyde dismutase
R. Rakhit, P. Cunningham, A. Furtos-Matei, S. Dahan, X.F. Qi, J.P. Crow, N.R. Cashman, L.H. Kondejewski, A. Chakrabartty
Oxidation-Iinduced Misfolding and Aggregation of Superoxide Dismutase and its Implications for Amyotrophic Lateral Sclerosis
J Biol Chem. (2002) 277: 47551-47556
R. Rakhit, J.P. Crow, J.R. Lepock, L.H. Kondejewski, N.R. Cashman, A. Chakrabartty
Monomeric Cu,Zn-Superoxide Dismutase is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis
J Biol Chem. (2004) 279: 15499-15504