Caprion

Finding proteins that hit the mark

Career Opportunities

Corporate culture

Caprion offers a dynamic and stimulating work environment, encouraging continuous innovation and the sharing of knowledge and ideas. We are proud to have built a strong team of highly motivated and skilled people.

We believe our success depends on the contributions and dedication of each employee. We are looking for individuals who are motivated by challenges and have the skills needed to evolve themselves and the company into the future.

Our world-class proteomics facility is situated within the Science Pavillion building of UQAM (Université de Québec à Montréal) in downtown Montréal.

Opportunities

ProteoCarta:

ImmuneCarta:

General:

 

 

PROTEOCARTA - MASS SPECTROMETRY RESEARCH ASSOCIATE


Position Summary:

Caprion is seeking a highly-motivated and enthusiastic Mass Spectrometry Research Associate with a strong background in mass spectrometry-based proteomics. This individual will play a key role in the label-free proteomics analysis of various biological matrices as well as quantitative MRM work for protein biomarkers and biologics/biosimilars. The major goals will be to carry out mass spectrometry analyses in a timely fashion, troubleshoot and resolve instrument issues in a GLP environment.

Specific Duties:

  • Analytical instrument operation, maintenance, troubleshooting and repair (Thermo Q Exactive, AB Sciex QTRAP and 6490 Agilent mass spectrometers).
  • Ensuring that system suitability tests meet criteria, filling out worksheets and log books.
  • Providing scientific and technical recommendations to improve the quality of results and the platform.
  • Organizing workload and meeting deadlines in a fast-paced, changing environment.
  • Work performed in a GLP environment.

Education:

  • B.Sc. or M.Sc. in analytical chemistry, chemistry or biochemistry (or equivalent).

Skills Requirements:

  • A minimum of 2 years of relevant experience operating electrospray-based LC/MS systems with a very high comfort level.
  • Excellent understanding of mass spectrometry and protein chemistry, as well as problem-solving and multitasking skills.
  • Must be self-motivated, highly organized and efficient, and be able to work both independently and as part of a team.
  • Must be able to successfully adapt in a rapidly changing environment.
  • Good written communication skills.
  • Experience working in industry is a big plus.

 

PROTEOCARTA - RESEARCH ASSOCIATE, SAMPLE PROCESSING


Position Summary:

Caprion is seeking a highly-motivated and enthusiastic Research Associate for its proteomics sample processing team. This individual will play a key role in performing a variety of techniques such as immuno-depletion, digestion and solid-phase extraction procedures on study samples (e.g. plasma, serum, CSF and other biological fluids) following Standard Operating Procedures (SOP) and Good Laboratory Practices (GLP).

Specific Duties:

  • Process biological samples for analysis by mass spectrometry
  • Execute work as per SOP, protocols or work instructions
  • Participate in troubleshooting, investigation and CAPA
  • Maintain study-related documentation according to GLP and regulatory guidance
  • Perform sample reception and tracking according to SOP
  • Monitor the performance of equipment and recording activities in logbooks
  • Perform general laboratory duties
  • Prepare and reviewing documentation for experiments
  • SOP writing
  • Perform work in a GLP environment and occasionally in a containment level 2 (CL2) environment

Education:

  • B.Sc. or M.Sc. in life sciences, chemistry or biochemistry (or equivalent)

Skills Requirements:

  • A minimum of 2 years of relevant experience;
  • Knowledge of sample processing for proteomics analysis, such as immuno-depletion and digestion techniques;
  • Knowledge and experience with chromatography-based techniques (eg., operating HPLC instruments);
  • Knowledge of procedures and protocols for containment of biohazardous material; ability to understand and apply safety procedures and guidelines;
  • Knowledge and understanding of GLP regulations;
  • Excellent time management and organizational skills to meet deadlines in a fast-paced, changing environment;
  • Ability to work independently, autonomously and as part of a team;
  • Skill to accurately test large numbers of samples with reliable repeatability.
  • Good record keeping, attention to details and commitment to achieve good quality work.
  • Experience working in industry is a plus.

 

PROTEOCARTA - BIOINFORMATICIAN / BIOSTATISTICIAN


Position Summary:

Caprion is seeking a highly motivated individual with experience in bioinformatics, biostatistics and proteomics. As part of the Bioinformatics group, the Bioinformatician/Biostatistician is involved in study design, quality control and analysis of proteomic mass spectrometry data, results visualization and reporting. The Bioinformatician/Biostatistican is responsible for the data processing of raw mass spectrometry data, choice of statistical methodology, the writing of the statistical analysis plan, carrying out the analyses and providing interpretations and conclusions that can be derived from the results. The successful candidate will also perform ad-hoc analyses and advise the scientific team on general bioinformatics and statistical questions and data analysis. The Bioinformatician/Biostatistician is expected to propose and implement new quality control and data analysis procedures and/or improve existing ones.

Responsibilities:

  • Provide significant input into the design of clinical proteomic studies.
  • Perform analysis of mass spectrometry data using the Elucidator software, Mascot, OMSSA, X!Tandem, Peptide/Protein Prophet, etc.
  • Evaluate protein annotations and proteomics mass spectrometry databases.
  • Provide biological annotations, and automate their extraction, parsing, transformation and loading from public or in-house databases.
  • Propose and implement novel quality control and data analysis procedures.
  • Provide clear visualization and summary of analysis results.
  • Provide scientific recommendations on how to improve the quality of the results and the throughput of the research platform.
  • Perform ad-hoc analysis to evaluate data quality or improve the understanding of the results.
  • Write formal Statistical Analysis Plans for complex studies.
  • Create randomization schemes for sample processing.
  • Perform statistical analyses of data (differential expression, classification) and interpret results to ensure validity of conclusions.
  • Write and review statistical sections for protocols and study reports.

Skills Requirements:

  • M.Sc. or Ph.D. in Biostatistics, Statistics, Bioinformatics or related field of study.
  • Three years of work experience in proteomics or related field.
  • Experience with a variety of statistical methods including general linear models (e.g., ANOVA), logistic regression, univariate and multivariate analyses, and longitudinal analyses.
  • Experience in predictive modeling, classification and discriminant analysis is strongly desirable.
  • Experience with R, C++, scripting language (PERL, Python, etc.).
  • Experience with relational databases such as Oracle, SQL Server or MySQL.
  • Solid understanding of molecular biology, proteomics and mass spectrometry.
  • Strong oral and written communication skills.
  • Good interpersonal skills and ability to work collaboratively as part of a fast paced research team.

 

IMMUNECARTA - RESEARCH ASSOCIATE


Position Summary:

Develops and qualifies/validates multi-parametric flow cytometry and ELISpot assays; Prepares and reviews experimental documentation for methods. Revises and writes procedures (SOP); Leads all aspects of a given development study (reagents, materials, schedule, documentation, etc). Participates in result interpretation and involves in problem-solving. Records associated documentation relevant to the tasks at hand as per appropriate SOP and applicable GLP regulations and GCLP guidelines.

Education:

  • B.Sc. or M.Sc.in life sciences, preferably in immunology.

Experience:

  • At least 3 years in a similar position.

Required Expertise and Skills:

  • Good knowledge of Multi-parametric flow cytometry assays (phenotyping, ICS, CFSE, etc);
  • Good knowledge of ELISpot an asset;
  • Skilled at problem-solving and multi-tasking;
  • Organized, rigorous and autonomous in the conduct of their work;
  • Experience in a GLP/GCLP environment.

Key Responsibilities:

  • Develops and /qualifies validates multi-parametric flow cytometry and ELISpot assays;
  • Prepares and reviews required documentation for experimentation;
  • Performs multi-parametric flow cytometry or ELISpot experiments;
  • Leads development studies (documentation, schedule, reagents, inventories, resources, etc);
  • Writes Method SOP;
  • Records associated documentation relevant to the tasks at hand as per appropriate SOP and applicable GLP regulations and GCLP guidelines.

 

IMMUNECARTA - RESEARCH ASSISTANT III


Position Summary:

Performs multi-parametric flow cytometry assays as per written procedures. Revises and writes procedures (SOP). Prepares and reviews experimental documentation for complex methods. Involved in the validation of multi-parametric assays. Leads all aspects of a given study (reagents, materials, schedule, documentation, etc). Records associated documentation relevant to the tasks at hand as per appropriate SOP and applicable GLP regulations and GCLP guidelines.

Education:

  • B.Sc. or M.Sc.in life sciences, preferably in immunology.

Experience:

  • At least 2 years in a similar position.

Required Expertise and Skills:

  • PBMC isolation and handling;
  • Multi-parametric flow cytometry assays (phenotyping, ICS, CFSE);
  • ELISpot an asset;
  • Working in a GLP/GCLP environment;
  • Organized, rigorous and autonomous in the conduct of their work;
  • Problem-solving;
  • Time management;
  • Knowledge and understating of the English language sufficient to write and carry out procedures and protocols.

Key Responsibilities:

  • Perform multi-parametric flow cytometry experiments;
  • Prepares and reviews required documentation for experimentation;
  • Leads flow cytometry studies (documentation, schedule, reagents, inventories, resources, etc);
  • Participates in the validation of complex methods (multi-parametric);
  • Writes Method SOP;
  • Records associated documentation relevant to the tasks at hand as per appropriate SOP and applicable GLP regulations and GCLP guidelines.

 

IMMUNECARTA - RESEARCH ASSISTANT (EVENINGS & WEEKENDS)


Position Summary:

Performs immune monitoring assays, blood sample processing and cryopreservation. Records associated documentation relevant to the tasks at hand as per appropriate SOP/CSP and applicable GLP regulations and GCLP guidelines. Performs reagent and material reception, tracking, and inventory. This is an evening position (~3 to ~11pm).

Education:

  • B.SC in life sciences, preferably in immunology, molecular biology, or biochemistry.

Skills:

  • Available to work in the evening (3-11pm);
  • Experience in PBMC isolation/cryopreservation and Flow cytometry an asset;
  • Experience working in a GLP/GCLP environment an asset;
  • Rigorous and autonomous in the conduct of their work;
  • Good organizational skills.

Key Responsibilities:

  • Conduct experiments (blood processing, cell cryopreservation);
  • Performs equipment maintenance, calibration and cleaning;
  • Performs reagent and material inventories;
  • Replenishes stocks of materials;
  • Performs biological sample inventory and files related documentation, when required;
  • Records associated documentation relevant to the tasks at hand as per appropriate SOP and applicable GLP regulations and GCLP guidelines.

 

IMMUNECARTA - DATA ANALYST


Position Summary:

The Data Analyst performs a variety of analytic functions within the Flow Cytometry Unit of Caprion Biosciences Inc. These functions include analysis and reporting of flow cytometry data and data from other platforms as needed. The analyst works under the supervision of the Manager of the Data Analysis Unit to ensure accurate and timely completion of data analysis. Maintains study-related documentation as per GLP/GCLP and regulatory guidance.

Education:

  • B.Sc. with experience, or M.Sc. in life sciences, preferably in bio-statistics or immunology.

Experience:

  • 1 year of experience in a similar position or equivalent.

Required Expertise and Skills:

  • Multiparametric flow cytometry statistical analysis (FlowJo and BD FACSDiva software);
  • Knowledge in statistical analysis softwares (R, Prism etc…).
  • Knowledge and understanding of GLP regulations sufficient to carry out GLP studies;
  • Knowledge and understanding of the English language sufficient to write and carry out procedures and protocols;
  • Strong computer skills and significant experience with Microsoft Excel, Word, and PowerPoint;
  • Detail-oriented person.

Key Responsibilities:

  • Analyzes data as per the Company’s SOPs;
  • Reviews data analyzed by other analysts and reports data as needed or instructed;
  • Assists as required in the organization of study data and associated information required for interim and final study reports;
  • Involved in implementation of new analytical/statistical tools to increase the data analysis throughput.

 

IMMUNECARTA - SENIOR RESEARCH SCIENTIST


Position Summary:

The Senior Research Scientist is responsible for ensuring high quality in the analysis and interpretation of data; He/She performs the analysis of data to ensure scientific integrity, compliance with SOP/CSP and applicable regulatory requirements. The Senior Research Scientist works closely with the Lead Scientist of the Data Analysis Unit, the Scientific Team and the Flow Cytometry Specialist to address technical/scientific and general project issues; He/She interacts with Quality Assurance to address quality issues and participates in client communications, preparation of scientific or technical materials such as reports, manuscripts, and posters along with the senior principal scientist.

Education:

  • Ph.D. or equivalent training in life sciences, preferably in immunology or virology.

Experience:

  • A minimum of 5 years of experience in a similar position.

Knowledge:

  • Deep knowledge of human immunology, immune monitoring methodologies and flow cytometry techniques;
  • Knowledge and understanding of GLP/GCLP regulations and other regulatory guidelines sufficient to carry out GLP/GCLP studies;
  • Experience with FlowJo is a must.

Skills:

  • Excellent data analysis and interpretation skills;
  • Approaches work methodically and systematically;
  • Establishes priorities from among a number of demands;
  • Skilled at working in a fast-paced and multi-tasking environment.

Key Responsibilities:

  • Performs analysis of data and ensures scientific integrity and compliance with SOP/CSP;
  • Interacts regularly with the Lead Scientist of the Data Analysis Unit, Scientific Team and Flow Cytometry Specialist to address project issues in a timely manner and to the satisfaction of the client;
  • Ensures that all study-related data is appropriately maintained;
  • Participates in the development of new in vitro assays as per client needs, including the assay qualification phase;
  • Participates in preparation of interim and final study reports as well as client communication with the coaching from Associate Director (Scientific Team) or Senior Principal Scientist
  • Provides scientific guidance as a high-quality resource person and contributes to the scientific leadership of ImmuneCarta Services.

 

SOP CUSTODIAN


Position Summary:

The SOP Custodian coordinates the maintenance and distribution of SOPs and related documents. He/She is also responsible for the formatting and filing of electronic and paper documentation. This position is also involved in study archiving documentation and data entry as needed.

Key Responsibilities:

  • Coordinate the control, distribution, and issuance of SOPs;
  • Maintain the training matrix;
  • Perform document formatting prior to issuance;
  • Perform study archiving (close-up, numbering, verification, filing, preparing table of contents, and filing appropriate archiving documentation);
  • Electronic and paper document filing;

Education:

  • DEC degree in administration, or life sciences.

Experience:

  • A minimum of 1 year of experience in a similar position or equivalent is required;
  • Having worked in a GLP or GCLP environment is a big plus.

Knowledge:

  • Excellent knowledge of Microsoft Word;
  • Good knowledge of Microsoft Excel;
  • Good communication skills in English and French.

Skills:

  • Strong organizational skills including attention to details;
  • Positive, professional attitude and ability to take initiative;
  • Ability to work both as part of a team and independently.

 


Interested candidates should submit their résumé by post or by email to:

Human Resources
Caprion
201 avenue Président-Kennedy, suite 3900
Montréal, Québec, Canada H2X 3Y7
careers@caprion.com

Please note, phone calls will not be accepted.  We thank all applicants for their interest, however, only those selected for an interview will be contacted.

© 2016 Caprion